Pfizer Integrative Biotechnology Group (IBG) is within the Oncology division of Pfizer Worldwide Research & Development and is located in Pearl River, NY.
IBG employs a multidisciplinary approach to target the cancer cell cycle and modulate the tumor microenvironment for the discovery and development of next generation oncology therapeutics and therapeutic combinations.
We are seeking a qualified candidate to join the group at a Senior Scientist level and contribute to drug discovery efforts leveraging functional genomics and advanced molecular biology strategies to elucidate drug mechanism of action and identifying drug combination opportunities.
The ideal candidate for this position will be a highly collaborative and motivated scientist with an interest to design and execute functional genomics screens.
S / he will establish strong scientific rationale for cancer cell model selection, establish molecular approaches for optimal in vitro and in vivo biological endpoint read-
outs, and contribute to hit prioritization and the design and execution of drug target validation and mechanism of action studies focused on prioritized hits in a collaborative team environment.
Design and execute CRISPR and / or RNAi functional genomic screens in vitro and in vivo for the discovery of novel development opportunities :
based assays for characterization of in vitro / in vivo target biology.
PHYSICAL / MENTAL REQUIREMENTS
Perform work in a laboratory setting
NON-STANDARD WORK SCHEDULE, TRAVEL OR ENVIRONMENT REQUIREMENTS
There will be less than 10% travel.
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EEO & Employment Eligibility
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Other Job Details :
Eligible for Relocation Package
Eligible for Employee Referral Bonus
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